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pentobarbital improves amounts of vortioxetine by rising metabolism. Modify Therapy/Keep track of Intently. Consider growing the vortioxetine dose when coadministered with potent CYP inducers for >fourteen days; never to exceed 3 times primary vortioxetine dose.Observe Closely (1)pentobarbital will lower the level or effect of tofacitinib by impact